So do not fear, for I am with you;
do not be dismayed, for I am your God.
I will strengthen you and help you;
I will uphold you with my righteous right hand.
Isaiah 41 : 10
I think it means that if we are frustrated or scared we can just call out to God and he will be there. God is always listening to your prayers.
I can apply this to my life with knowing God is always listening to my concerns and worries.